Hover over the bar plot to get the GO term. Differentially targeted genes and TFs were computed by comparing a cancer network to all other cancers.
Tool description
PANDA reconstructs a gene regulatory network using TF PPI, TF DNA binding motif, and gene expression samples. LIONESS reconstructs patient-specific PANDA networks for each gene expression sample.
To download patient-specific networks, you can check the phenotypic information of the TCGA dataset. You can also select the networks by
clinical variables or download all the samples in a single file.
The variable Samples indicates the number of samples used for network reconstruction. For single-sample networks, clicking the number of samples links to the phenotypic variable table and the individual
networks. The number in the Sample variable and the phenotypic variable table may be different because the table can include samples from other studies. For example, in colon cancer, 444 TCGA samples were
used to build LIONESS networks in a first study and 445 samples were used for a more recent study. The superset of both TCGA samples is comprised of 487 samples, which is the size of the pheotypic variables
table. This discrepancy is due to different pre-processinng techniques, inclusion/exclusion criteria, and sample quality-control.
Variable description
This is a description of the primary clinical variables of the gene expression samples that were used to generate the gene regulatory network.
Sample | Gender | Race | Stage | Vital status | Age | Days to last follow up | Tumor ID | Network |
---|---|---|---|---|---|---|---|---|
TCGA-A3-3308-01A | FEMALE | WHITE | Stage III | Alive | 77 | 16 | KIRC | |
TCGA-CJ-5680-01A | FEMALE | WHITE | Stage IV | Dead | 65 | [Not Available] | KIRC | |
TCGA-CZ-5465-01A | FEMALE | [Not Available] | Stage III | Alive | 76 | 1377 | KIRC | |
TCGA-B0-5096-01A | FEMALE | WHITE | Stage III | Dead | 72 | [Not Available] | KIRC | |
TCGA-BP-4964-01A | FEMALE | WHITE | Stage I | Alive | 54 | 1862 | KIRC | |
TCGA-CJ-4644-01A | FEMALE | WHITE | Stage IV | Dead | 48 | [Not Available] | KIRC | |
TCGA-BP-4169-01A | FEMALE | WHITE | Stage II | Dead | 76 | [Not Available] | KIRC | |
TCGA-CJ-4634-01A | FEMALE | WHITE | Stage I | Alive | 60 | 1820 | KIRC | |
TCGA-BP-4774-01A | FEMALE | WHITE | Stage I | Alive | 57 | 1885 | KIRC | |
TCGA-CZ-4856-01A | FEMALE | WHITE | Stage I | Alive | 62 | 18 | KIRC |