A set of networks in normal and cancer tissues have been generated using the same processing pipeline: The normal tissue networks are the ones that were generated in Sonwane et al.
and available in the tissues
section, and the cancer networks are available in the downlaod
section. The processing pipeline can can be accessed in netbooks
under "Generating 26 cancer gene regulatory network using TCGA datasets".
To plot a differential network, first the first network (e.g., cancer) and the second network (e.g., normal tissue) can be selected from the dropdown menu and after clicking submit, the differential network is plotted by the specified parameters. Selecting 'weighted edges' option allows to plot edge thickness by the edge weight. Positive edge weights (network 2 > network 1) are plotted in green and negative edge weights (network 1 > network 2) are plotted in red.