Edges

Value:

Weighted edges

Node scaling
No scaling
Scale by targeting
Scale by betweeness

Selection
No selection

by gene


by TF


by GO


by GWAS



Save


Edge weights table
Source Target Edge weight

max. 500 megabytes



The network format should be an adjacency matrix representing a set of regulators (TFs/miRNA) in the rows and a set of target genes in the columns, with regulator names as row names and gene names as columns names. Here is an example file for reference.

After uploading the network in the first tab (1. Upload network), you can visualize the network in the second tab (2. Visualize network) by clicking submit after selecting the parameters of interest. Or you can switch to the third tab (3. Compute targeting) to perform an exploratory analysis of the network including enrichment and drug repurposing analysis.








Genes

Value:


Selection
No selection

by gene


by GO


by GWAS


TFs

Value:




Analysis
Analyze the submitted list of targeted genes/TFs for downstream analysis.

1. Enrichment analysis
Enrich TFs


2. Drug repurposing
By gene By TF



Gene Targeting score
Gene Targeting score
TF Targeting score
Regulator Targeting score