Edges

Value:

weights
weights
Weighted edges

Node scaling
No scaling

Selection
No selection

by gene


by TF


by GO


by GWAS



Save
as png


Edge weights table
Source Target Edge weight

max. 500 megabytes



This tool allows users to upload their own network, visualize the network structure, and compute targeting scores for genes and TFs in the network. The network should be formatted as an adjacency matrix representing a set of regulators (TFs/miRNA) in the rows and a set of target genes in the columns, with regulator names as row names and gene names as columns names. See this example file for reference.

After uploading the network in the first tab (1. Upload network), you can visualize the network in the second tab (2. Visualize network) by clicking submit after selecting the parameters of interest. Or you can switch to the third tab (3. Compute targeting) to perform an exploratory analysis of the network including enrichment and drug repurposing analysis.

Genes

Value:


Selection
No selection

by gene


by GO


by GWAS


TFs

Value:




Analysis
Analyze the submitted list of targeted genes/TFs for downstream analysis.

1. Enrichment analysis
Enrich TFs


2. Drug repurposing
By gene By TF



Gene Targeting score
Gene Targeting score
TF Targeting score
Regulator Targeting score