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  • Changelog
    v0.1 cell line networks
    v0.2 aggregate tissue networks
    v0.3 TF enrichement tool
    v0.4 single-sample tissue networks
    v0.5 CLUEreg tool
    v0.6 colon cancer networks
    v0.7 drug networks
    v0.7.1 API v1
    v0.8 liver, cervix, and breast cancer networks
    v0.9 miRNA tissue networks
    v0.9.1 bootstrap 5
    v1.0 glioblastoma networks
    v1.0.1 drug combinations
    v1.1 Cell line networks
    v1.2 User upload network
    v1.2.1 Gene targeting table
    v1.2.2 DRAGON miRNA network
    v1.3 Network comparison
    v1.3.1 Guided tours
    v1.4.0 CCLE multi-omic map
    v1.5.0 EGRET networks
    v1.6.0 BONOBO networks
    v1.7.0 tcga-data-nf networks

    Small molecule drugs

    The small molecule resource includes 173,013 TF and gene targeting scores for 2,858 drugs tested in different doses, cell lines, and sampling times inferred using data from CLUE and DRH.

    Differentially targeted TFs and genes per drug on a logarithm scale with bubble size equal to the logarithm of the number of samples per drug. Click on the bubble plot to filter the table below.

    # Drug Number of samples
    Average TF targeting
    Average gene targeting
    Mechanism of action Indication
    Contact

    Department of Biostatistics
    Harvard T.H. Chan School of Public Health

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