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  • Changelog
    v0.1 cell line networks
    v0.2 aggregate tissue networks
    v0.3 TF enrichement tool
    v0.4 single-sample tissue networks
    v0.5 CLUEreg tool
    v0.6 colon cancer networks
    v0.7 drug networks
    v0.7.1 API v1
    v0.8 liver, cervix, and breast cancer networks
    v0.9 miRNA tissue networks
    v0.9.1 bootstrap 5
    v1.0 glioblastoma networks

    Lung cancer networks

    Data sets 0 Networks
      Colon cancer 2 Cervix cancer 1 Breast cancer 1 Liver cancer 1 GBM 3 Kidney cancer 1 Lung cancer 1 PDAC 1

    To get the full list of phenotypic variables, please check the menu below.

    Tool description

    Like PANDA, OTTER reconstructs a gene regulatory network from the TF PPI, TF DNA binding motif, and gene expression samples. OTTER formulates network inference as a well-defined objective function that optimizes the graph matching of the three network priors. Check the phenotypic information for the clinical variables of the samples that were used to reconstruct the network.

    # Tissue Tool netZoo release Network
    PPI
    Motif Expression TFs Genes Data Samples Precision
    Ref.

    Variable description

    This is a description of the primary clinical variables of the gene expression samples that were used to generate the gene regulatory network.

    Sample
    Gender Race Ethnicity Weight
    Height
    Anatomic location
    Stage
    Diagnosis Vital status Time
    Age
    Sample Gender Race Ethnicity Weight Height Anatomic location Stage Diagnosis Vital status Time to event Age
    Contact

    Department of Biostatistics
    Harvard T.H. Chan School of Public Health

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