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    v0.1 cell line networks
    v0.2 aggregate tissue networks
    v0.3 TF enrichement tool
    v0.4 single-sample tissue networks
    v0.5 CLUEreg tool
    v0.6 colon cancer networks
    v0.7 drug networks
    v0.7.1 API v1
    v0.8 liver, cervix, and breast cancer networks
    v0.9 miRNA tissue networks
    v0.9.1 bootstrap 5
    v1.0 glioblastoma networks

    Tool description

    PANDA reconstructs a gene regulatory network using TF PPI, TF DNA binding motif as regulation prior, and gene expression samples. PUMA reconstructs a gene regulatory network with miRNA as regulators using gene expression samples and miRNA predicted targets by miRanda or TargetScan as regulation priors. The Regulator-regulator interaction matrix is set to the identity matrix in the algorithm. Check the phenotypic information for the clinical variables of the samples that were used to reconstruct the network.

    Publication
    Please check the reference Sonawane et al. (2017) at the following link.
    Publication
    Please check the reference Kuijjer et al. (2020) at the following link.
    Publication
    Please check the reference Kuijjer et al. (2020) at the following link.
    # Tissue Tool netZoo release Network
    		PPI
    		 Reg. prior Expr.
    		 Reg.
    		 nReg
    		 Genes Samples Precision
    		 Reference
    1 Ovary PANDA netZooM 0.1
    coR
    		 Motif TF 644 30243 108 D
    2 Ovary PUMA netZooM 0.3
    coR
    		 - miRanda miRNA 643 16161 334 D
    3 Ovary PUMA netZooM 0.3
    coR
    		 - TargetScan miRNA 643 16161 334 D

    Variable description

    This is a description of the primary clinical variables of the gene expression samples that were used to generate the gene regulatory network.

    Sample Subject Gender
    		Age DTH-HRDY
    		 SMAT-SSCR
    		 SMRIN
    		 SMTS
    		 SMTSD
    		 SMUBRID
    		 SMTSISCH
    GTEX-1117F-2226-SM-5N9CH GTEX-1117F 2 60-69 4 1 6.6 Ovary Ovary 2119 1326
    GTEX-11DXX-1426-SM-5GIDU GTEX-11DXX 2 60-69 0 1 7.3 Ovary Ovary 2119 117
    GTEX-11EM3-1726-SM-5N9D1 GTEX-11EM3 2 20-29 0 0 8.8 Ovary Ovary 2119 194
    GTEX-11EMC-1726-SM-5H11P GTEX-11EMC 2 60-69 2 1 7.6 Ovary Ovary 2119 731
    GTEX-11GSP-0226-SM-5A5KV GTEX-11GSP 2 60-69 2 0 7.5 Ovary Ovary 2119 764
    GTEX-11I78-1926-SM-59878 GTEX-11I78 2 50-59 0 1 8.6 Ovary Ovary 2119 130
    GTEX-11P81-1526-SM-5P9GS GTEX-11P81 2 30-39 0 0 8.5 Ovary Ovary 2119 282
    GTEX-11VI4-1026-SM-5EQM1 GTEX-11VI4 2 40-49 0 0 8.3 Ovary Ovary 2119 143
    GTEX-11XUK-1626-SM-5GU5O GTEX-11XUK 2 40-49 0 0 7.6 Ovary Ovary 2119 167
    GTEX-11ZTS-1926-SM-5CVLA GTEX-11ZTS 2 60-69 2 1 6.4 Ovary Ovary 2119 683
    GTEX-11ZTT-1826-SM-5CVLN GTEX-11ZTT 2 60-69 0 1 6.6 Ovary Ovary 2119 207
    GTEX-11ZVC-1426-SM-5EGGA GTEX-11ZVC 2 50-59 2 1 7.2 Ovary Ovary 2119 553
    GTEX-1269C-1826-SM-5N9E1 GTEX-1269C 2 60-69 2 1 5.7 Ovary Ovary 2119 827
    GTEX-12WSB-2226-SM-5GCOS GTEX-12WSB 2 60-69 4 1 5.9 Ovary Ovary 2119 1158
    GTEX-12WSD-2726-SM-59HLR GTEX-12WSD 2 60-69 2 1 7.1 Ovary Ovary 2119 551
    GTEX-12WSG-1426-SM-5FQUK GTEX-12WSG 2 50-59 0 0 6.6 Ovary Ovary 2119 355
    GTEX-12WSJ-1226-SM-5LU91 GTEX-12WSJ 2 40-49 0 0 8.1 Ovary Ovary 2119 144
    GTEX-12WSK-1926-SM-5LZVK GTEX-12WSK 2 40-49 0 1 7.7 Ovary Ovary 2119 193
    GTEX-12ZZX-2026-SM-5LZV9 GTEX-12ZZX 2 40-49 1 1 6 Ovary Ovary 2119 679
    GTEX-1313W-2726-SM-5P9IX GTEX-1313W 2 50-59 2 1 7.1 Ovary Ovary 2119 730
    GTEX-131YS-2226-SM-5P9G8 GTEX-131YS 2 60-69 2 0 6.7 Ovary Ovary 2119 1006
    GTEX-132AR-1426-SM-5IFF1 GTEX-132AR 2 50-59 0 0 7.9 Ovary Ovary 2119 104
    GTEX-133LE-1226-SM-5IFGC GTEX-133LE 2 20-29 0 0 7.6 Ovary Ovary 2119 174
    GTEX-1399S-2126-SM-5J2MH GTEX-1399S 2 30-39 0 1 8.2 Ovary Ovary 2119 143
    GTEX-1399U-1726-SM-5P9J4 GTEX-1399U 2 50-59 0 1 8.3 Ovary Ovary 2119 212
    GTEX-139D8-2426-SM-5KM3A GTEX-139D8 2 30-39 0 1 6.8 Ovary Ovary 2119 465
    GTEX-13D11-1126-SM-5KLYS GTEX-13D11 2 50-59 0 1 7.2 Ovary Ovary 2119 120
    GTEX-13FTX-0926-SM-5IFF7 GTEX-13FTX 2 20-29 0 0 6.3 Ovary Ovary 2119 174
    GTEX-13N11-0526-SM-5IJFI GTEX-13N11 2 50-59 0 0 7.5 Ovary Ovary 2119 167
    GTEX-13O3O-2726-SM-5KM35 GTEX-13O3O 2 60-69 3 0 5.9 Ovary Ovary 2119 877
    GTEX-13OVI-0726-SM-5L3DD GTEX-13OVI 2 60-69 0 1 8 Ovary Ovary 2119 163
    GTEX-13OVJ-2426-SM-5KM3I GTEX-13OVJ 2 50-59 2 1 6.8 Ovary Ovary 2119 1167
    GTEX-13PL7-2326-SM-5L3FY GTEX-13PL7 2 60-69 0 1 6.7 Ovary Ovary 2119 176
    GTEX-13PVR-1226-SM-5RQJ2 GTEX-13PVR 2 60-69 0 1 8.2 Ovary Ovary 2119 137
    GTEX-13QBU-1526-SM-5LU3W GTEX-13QBU 2 40-49 0 1 7.3 Ovary Ovary 2119 213
    GTEX-13QIC-1526-SM-5IJFL GTEX-13QIC 2 60-69 2 1 6.4 Ovary Ovary 2119 826
    GTEX-13U4I-2126-SM-5LU55 GTEX-13U4I 2 40-49 0 1 7.6 Ovary Ovary 2119 454
    GTEX-13VXT-1526-SM-5LU3J GTEX-13VXT 2 20-29 0 1 6.3 Ovary Ovary 2119 533
    GTEX-13W3W-1526-SM-5LU5I GTEX-13W3W 2 60-69 0 1 7.7 Ovary Ovary 2119 235
    GTEX-13X6H-1026-SM-5SIBE GTEX-13X6H 2 50-59 0 1 8.6 Ovary Ovary 2119 218
    GTEX-145ME-1226-SM-5SIB6 GTEX-145ME 2 40-49 0 1 7.3 Ovary Ovary 2119 296
    GTEX-146FH-2526-SM-5Q5BP GTEX-146FH 2 50-59 0 1 6.7 Ovary Ovary 2119 490
    GTEX-14AS3-1326-SM-5RQJE GTEX-14AS3 2 40-49 0 0 5.9 Ovary Ovary 2119 131
    GTEX-OHPK-2426-SM-3MJGH GTEX-OHPK 2 50-59 0 1 8.1 Ovary Ovary 2119 521
    GTEX-OHPL-2426-SM-48TDN GTEX-OHPL 2 60-69 0 1 5.9 Ovary Ovary 2119 141
    GTEX-P4PP-2426-SM-3P61L GTEX-P4PP 2 30-39 0 1 7.4 Ovary Ovary 2119 143
    GTEX-P4QT-2426-SM-3NMCL GTEX-P4QT 2 50-59 0 1 7.3 Ovary Ovary 2119 156
    GTEX-P78B-1926-SM-3P616 GTEX-P78B 2 40-49 1 7.7 Ovary Ovary 2119 598
    GTEX-PLZ4-2826-SM-3P617 GTEX-PLZ4 2 50-59 1 6 Ovary Ovary 2119 730
    GTEX-POMQ-1426-SM-3P61D GTEX-POMQ 2 20-29 0 1 7.1 Ovary Ovary 2119 258
    GTEX-PWCY-1326-SM-48TCU GTEX-PWCY 2 20-29 0 0 7.5 Ovary Ovary 2119 249
    GTEX-PWN1-2426-SM-48TDD GTEX-PWN1 2 40-49 0 0 7.7 Ovary Ovary 2119 157
    GTEX-PWOO-1726-SM-48TDC GTEX-PWOO 2 40-49 0 0 8.5 Ovary Ovary 2119 216
    GTEX-PX3G-2426-SM-48TZZ GTEX-PX3G 2 20-29 0 0 8.3 Ovary Ovary 2119 185
    GTEX-Q734-0726-SM-48TZP GTEX-Q734 2 40-49 0 1 8.5 Ovary Ovary 2119 66
    GTEX-QCQG-1426-SM-48U22 GTEX-QCQG 2 50-59 0 1 7.7 Ovary Ovary 2119 236
    GTEX-QVJO-3126-SM-4R1KC GTEX-QVJO 2 60-69 4 1 6.3 Ovary Ovary 2119 1287
    GTEX-R55G-1526-SM-48FER GTEX-R55G 2 40-49 0 0 7.4 Ovary Ovary 2119 138
    GTEX-RTLS-2326-SM-46MUH GTEX-RTLS 2 60-69 4 1 7 Ovary Ovary 2119 690
    GTEX-RU1J-0826-SM-46MUU GTEX-RU1J 2 20-29 0 1 7.5 Ovary Ovary 2119 239
    GTEX-RU72-2226-SM-46MUE GTEX-RU72 2 50-59 2 1 7 Ovary Ovary 2119 521
    GTEX-RWS6-1026-SM-47JXD GTEX-RWS6 2 60-69 0 1 8.2 Ovary Ovary 2119 181
    GTEX-S32W-1226-SM-4AD67 GTEX-S32W 2 50-59 0 0 6.5 Ovary Ovary 2119 322
    GTEX-S341-0726-SM-4AD5R GTEX-S341 2 40-49 0 0 7.3 Ovary Ovary 2119 182
    GTEX-S4P3-0926-SM-4AD54 GTEX-S4P3 2 50-59 0 1 6.8 Ovary Ovary 2119 193
    GTEX-S4UY-1026-SM-4AD53 GTEX-S4UY 2 40-49 0 1 8.2 Ovary Ovary 2119 421
    GTEX-S7SF-1326-SM-4AD4P GTEX-S7SF 2 20-29 0 0 6 Ovary Ovary 2119 321
    GTEX-T2IS-2026-SM-4DM6W GTEX-T2IS 2 20-29 1 1 6.5 Ovary Ovary 2119 1208
    GTEX-T5JW-0426-SM-4DM7M GTEX-T5JW 2 20-29 0 1 6.8 Ovary Ovary 2119 153
    GTEX-T6MO-1126-SM-4DM5D GTEX-T6MO 2 40-49 0 1 7.2 Ovary Ovary 2119 147
    GTEX-TML8-0926-SM-4DXSJ GTEX-TML8 2 40-49 0 1 7.8 Ovary Ovary 2119 154
    GTEX-TMMY-1726-SM-4DXTD GTEX-TMMY 2 40-49 0 1 7.9 Ovary Ovary 2119 445
    GTEX-TSE9-2226-SM-4DXUR GTEX-TSE9 2 60-69 0 1 7.2 Ovary Ovary 2119 1192
    GTEX-U3ZN-1026-SM-4DXTC GTEX-U3ZN 2 30-39 0 0 7.9 Ovary Ovary 2119 129
    GTEX-UJHI-1226-SM-4IHLR GTEX-UJHI 2 50-59 0 0 6.8 Ovary Ovary 2119 241
    GTEX-W5WG-0926-SM-4RTX9 GTEX-W5WG 2 50-59 0 1 8.3 Ovary Ovary 2119 226
    GTEX-WEY5-0626-SM-4LMIA GTEX-WEY5 2 40-49 0 1 8 Ovary Ovary 2119 217
    GTEX-WI4N-2526-SM-4OOSE GTEX-WI4N 2 40-49 0 1 7.6 Ovary Ovary 2119 783
    GTEX-WWYW-2726-SM-4MVOP GTEX-WWYW 2 50-59 3 1 6.5 Ovary Ovary 2119 851
    GTEX-WXYG-1426-SM-4ONCK GTEX-WXYG 2 50-59 0 1 7.3 Ovary Ovary 2119 179
    GTEX-WYBS-2426-SM-4ONDI GTEX-WYBS 2 60-69 0 2 6.6 Ovary Ovary 2119 943
    GTEX-WYVS-1526-SM-4OND4 GTEX-WYVS 2 40-49 0 1 8.2 Ovary Ovary 2119 280
    GTEX-X15G-1726-SM-4PQZN GTEX-X15G 2 50-59 0 1 7.5 Ovary Ovary 2119 303
    GTEX-X4EO-2426-SM-4QASD GTEX-X4EO 2 60-69 3 2 6.9 Ovary Ovary 2119 832
    GTEX-X8HC-2726-SM-46MUA GTEX-X8HC 2 50-59 0 1 7.2 Ovary Ovary 2119 832
    GTEX-XMD3-2326-SM-4AT5H GTEX-XMD3 2 50-59 0 1 6 Ovary Ovary 2119 1407
    GTEX-XUJ4-1326-SM-4BOQ9 GTEX-XUJ4 2 60-69 0 1 8.6 Ovary Ovary 2119 134
    GTEX-XUW1-0126-SM-4BOOQ GTEX-XUW1 2 50-59 0 0 7.7 Ovary Ovary 2119 281
    GTEX-XUZC-1026-SM-4BOPY GTEX-XUZC 2 30-39 0 1 7.6 Ovary Ovary 2119 122
    GTEX-XV7Q-1426-SM-4BRWA GTEX-XV7Q 2 40-49 0 1 7.9 Ovary Ovary 2119 101
    GTEX-XYKS-1726-SM-4E3IO GTEX-XYKS 2 60-69 0 0 7.8 Ovary Ovary 2119 210
    GTEX-Y114-1726-SM-4TT7U GTEX-Y114 2 50-59 0 1 8.4 Ovary Ovary 2119 176
    GTEX-Y3IK-2026-SM-4YCDG GTEX-Y3IK 2 50-59 0 0 7.7 Ovary Ovary 2119 124
    GTEX-YB5K-1426-SM-5IFIB GTEX-YB5K 2 40-49 0 1 8 Ovary Ovary 2119 234
    GTEX-YFC4-2726-SM-5IFJW GTEX-YFC4 2 40-49 1 2 7 Ovary Ovary 2119 836
    GTEX-YJ8O-1026-SM-5CVM5 GTEX-YJ8O 2 40-49 1 1 6.1 Ovary Ovary 2119 731
    GTEX-ZAJG-2726-SM-5S2MU GTEX-ZAJG 2 50-59 3 1 7.1 Ovary Ovary 2119 848
    GTEX-ZC5H-2026-SM-5CVN2 GTEX-ZC5H 2 40-49 0 1 6.8 Ovary Ovary 2119 297
    GTEX-ZLWG-0926-SM-4WWC3 GTEX-ZLWG 2 50-59 0 0 8.1 Ovary Ovary 2119 103
    GTEX-ZP4G-0626-SM-4WWF1 GTEX-ZP4G 2 20-29 0 1 6.7 Ovary Ovary 2119 188
    GTEX-ZPIC-1426-SM-4WWCP GTEX-ZPIC 2 40-49 0 0 8.8 Ovary Ovary 2119 151
    GTEX-ZV6S-1426-SM-59HKX GTEX-ZV6S 2 40-49 0 1 8.2 Ovary Ovary 2119 387
    GTEX-ZVT2-0326-SM-5E44G GTEX-ZVT2 2 50-59 0 1 9 Ovary Ovary 2119 90
    GTEX-ZVT3-2626-SM-5GU5L GTEX-ZVT3 2 60-69 2 1 7 Ovary Ovary 2119 642
    GTEX-ZYFG-1726-SM-5GZZB GTEX-ZYFG 2 60-69 0 0 7.9 Ovary Ovary 2119 108
    GTEX-ZYWO-1926-SM-5E456 GTEX-ZYWO 2 40-49 0 0 7.3 Ovary Ovary 2119 155
    GTEX-ZYY3-2726-SM-5EGH4 GTEX-ZYY3 2 60-69 4 1 6.1 Ovary Ovary 2119 538
    GTEX-ZZPU-2126-SM-5EGIU GTEX-ZZPU 2 50-59 0 0 7.8 Ovary Ovary 2119 231
    Contact

    Department of Biostatistics
    Harvard T.H. Chan School of Public Health

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