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    v0.1 cell line networks
    v0.2 aggregate tissue networks
    v0.3 TF enrichement tool
    v0.4 single-sample tissue networks
    v0.5 CLUEreg tool
    v0.6 colon cancer networks
    v0.7 drug networks
    v0.7.1 API v1
    v0.8 liver, cervix, and breast cancer networks
    v0.9 miRNA tissue networks
    v0.9.1 bootstrap 5
    v1.0 glioblastoma networks

    Tool description

    PANDA reconstructs a gene regulatory network using TF PPI, TF DNA binding motif as regulation prior, and gene expression samples. PUMA reconstructs a gene regulatory network with miRNA as regulators using gene expression samples and miRNA predicted targets by miRanda or TargetScan as regulation priors. The Regulator-regulator interaction matrix is set to the identity matrix in the algorithm. Check the phenotypic information for the clinical variables of the samples that were used to reconstruct the network.

    Publication
    Please check the reference Sonawane et al. (2017) at the following link.
    Publication
    Please check the reference Kuijjer et al. (2020) at the following link.
    Publication
    Please check the reference Kuijjer et al. (2020) at the following link.
    # Tissue Tool netZoo release Network
    		PPI
    		 Reg. prior Expr.
    		 Reg.
    		 nReg
    		 Genes Samples Precision
    		 Reference
    1 Prostate PANDA netZooM 0.1
    coR
    		 Motif TF 644 30243 119 D
    2 Prostate PUMA netZooM 0.3
    coR
    		 - miRanda miRNA 643 16161 124 D
    3 Prostate PUMA netZooM 0.3
    coR
    		 - TargetScan miRNA 643 16161 124 D

    Variable description

    This is a description of the primary clinical variables of the gene expression samples that were used to generate the gene regulatory network.

    Sample Subject Gender
    		Age DTH-HRDY
    		 SMAT-SSCR
    		 SMRIN
    		 SMTS
    		 SMTSD
    		 SMUBRID
    		 SMTSISCH
    GTEX-111CU-1526-SM-5N9FS GTEX-111CU 1 50-59 0 1 5.7 Prostate Prostate 2367 103
    GTEX-111FC-2026-SM-5GZYO GTEX-111FC 1 60-69 1 2 5.8 Prostate Prostate 2367 1121
    GTEX-111YS-1726-SM-5GIED GTEX-111YS 1 60-69 0 1 6.3 Prostate Prostate 2367 179
    GTEX-117YW-1426-SM-5EGGO GTEX-117YW 1 50-59 3 1 5.9 Prostate Prostate 2367 884
    GTEX-117YX-1526-SM-5H12T GTEX-117YX 1 50-59 0 1 6.1 Prostate Prostate 2367 110
    GTEX-11DXZ-1826-SM-5H12Y GTEX-11DXZ 1 50-59 0 0 7.5 Prostate Prostate 2367 316
    GTEX-11DYG-2526-SM-5N9BB GTEX-11DYG 1 60-69 2 3 5.7 Prostate Prostate 2367 886
    GTEX-11EQ9-1726-SM-5HL6U GTEX-11EQ9 1 30-39 2 1 7.6 Prostate Prostate 2367 130
    GTEX-11NSD-0826-SM-5986S GTEX-11NSD 1 20-29 0 1 7.5 Prostate Prostate 2367 91
    GTEX-11O72-2726-SM-5HL6K GTEX-11O72 1 40-49 2 3 6.1 Prostate Prostate 2367 1012
    GTEX-11OF3-1726-SM-5GU5Q GTEX-11OF3 1 60-69 2 3 5.9 Prostate Prostate 2367 817
    GTEX-11P7K-0626-SM-5985Z GTEX-11P7K 1 30-39 0 1 7.9 Prostate Prostate 2367 114
    GTEX-11P82-1126-SM-5BC5K GTEX-11P82 1 20-29 1 1 7.2 Prostate Prostate 2367 171
    GTEX-11TT1-2026-SM-5EQM8 GTEX-11TT1 1 20-29 0 1 8.2 Prostate Prostate 2367 107
    GTEX-11TUW-2126-SM-5GU7B GTEX-11TUW 1 60-69 2 2 5.8 Prostate Prostate 2367 781
    GTEX-11WQK-2726-SM-5EQMU GTEX-11WQK 1 50-59 2 2 5.9 Prostate Prostate 2367 814
    GTEX-11ZUS-2126-SM-5N9E6 GTEX-11ZUS 1 30-39 1 2 5.7 Prostate Prostate 2367 1413
    GTEX-12696-2226-SM-5EQ65 GTEX-12696 1 60-69 3 2 6.7 Prostate Prostate 2367 571
    GTEX-12BJ1-1226-SM-5LUAE GTEX-12BJ1 1 60-69 0 1 8.3 Prostate Prostate 2367 129
    GTEX-12C56-1326-SM-5FQSV GTEX-12C56 1 20-29 0 0 6.9 Prostate Prostate 2367 223
    GTEX-12ZZZ-2026-SM-5LZWJ GTEX-12ZZZ 1 60-69 2 3 6 Prostate Prostate 2367 878
    GTEX-13111-1326-SM-5GCNO GTEX-13111 1 50-59 0 1 7 Prostate Prostate 2367 306
    GTEX-131XF-1926-SM-5DUW4 GTEX-131XF 1 60-69 0 1 6 Prostate Prostate 2367 303
    GTEX-132NY-2826-SM-5P9G2 GTEX-132NY 1 60-69 1 2 6.6 Prostate Prostate 2367 616
    GTEX-132QS-1126-SM-5P9GC GTEX-132QS 1 60-69 0 1 7.6 Prostate Prostate 2367 1573
    GTEX-1399R-0526-SM-5IJEF GTEX-1399R 1 30-39 0 1 7.9 Prostate Prostate 2367 91
    GTEX-1399T-1226-SM-5P9J5 GTEX-1399T 1 60-69 2 2 6.3 Prostate Prostate 2367 783
    GTEX-139T6-1526-SM-5P9G6 GTEX-139T6 1 50-59 0 1 6.7 Prostate Prostate 2367 191
    GTEX-13FHO-2826-SM-5K7ZA GTEX-13FHO 1 60-69 0 2 6 Prostate Prostate 2367 764
    GTEX-13FTW-1226-SM-5LZZ1 GTEX-13FTW 1 40-49 0 1 7.6 Prostate Prostate 2367 181
    GTEX-13FXS-2826-SM-5LZYC GTEX-13FXS 1 50-59 2 2 6.2 Prostate Prostate 2367 717
    GTEX-13G51-2326-SM-5LZXV GTEX-13G51 1 60-69 2 2 5.8 Prostate Prostate 2367 832
    GTEX-13N2G-1826-SM-5KM1I GTEX-13N2G 1 60-69 2 1 6.2 Prostate Prostate 2367 563
    GTEX-13NYS-1026-SM-5KLZT GTEX-13NYS 1 60-69 4 2 6.1 Prostate Prostate 2367 951
    GTEX-13O21-1126-SM-5N9EV GTEX-13O21 1 50-59 0 1 5.7 Prostate Prostate 2367 194
    GTEX-13O61-1726-SM-5KM46 GTEX-13O61 1 60-69 0 0 6.8 Prostate Prostate 2367 181
    GTEX-13OW8-0426-SM-5J2NR GTEX-13OW8 1 60-69 2 2 6 Prostate Prostate 2367 1044
    GTEX-13RTJ-2126-SM-5S2PZ GTEX-13RTJ 1 60-69 4 1 6.3 Prostate Prostate 2367 917
    GTEX-144GM-0826-SM-5O98R GTEX-144GM 1 20-29 0 1 6.9 Prostate Prostate 2367 227
    GTEX-145LT-0626-SM-5O99E GTEX-145LT 1 40-49 0 1 6.1 Prostate Prostate 2367 154
    GTEX-145LU-2126-SM-5Q5E9 GTEX-145LU 1 50-59 2 1 6 Prostate Prostate 2367 1069
    GTEX-145LV-1226-SM-5S2QH GTEX-145LV 1 50-59 0 1 6.3 Prostate Prostate 2367 426
    GTEX-146FQ-1726-SM-5QGPX GTEX-146FQ 1 30-39 0 1 6 Prostate Prostate 2367 538
    GTEX-1477Z-2226-SM-5QGPG GTEX-1477Z 1 60-69 4 2 6.1 Prostate Prostate 2367 729
    GTEX-148VJ-1826-SM-5Q5DV GTEX-148VJ 1 70-79 2 1 6.2 Prostate Prostate 2367 1097
    GTEX-14ABY-0726-SM-5Q5DF GTEX-14ABY 1 50-59 2 2 5.7 Prostate Prostate 2367 1299
    GTEX-14BMV-2326-SM-5RQJ4 GTEX-14BMV 1 50-59 2 2 5.7 Prostate Prostate 2367 660
    GTEX-14C5O-2826-SM-5RQI6 GTEX-14C5O 1 60-69 4 2 6.8 Prostate Prostate 2367 773
    GTEX-14E6E-1126-SM-5S2R4 GTEX-14E6E 1 30-39 0 1 7.6 Prostate Prostate 2367 143
    GTEX-NFK9-2226-SM-3MJGP GTEX-NFK9 1 40-49 0 1 7.5 Prostate Prostate 2367 382
    GTEX-NPJ8-2426-SM-3MJHL GTEX-NPJ8 1 40-49 4 2 6.7 Prostate Prostate 2367 356
    GTEX-OIZH-2026-SM-3NB1M GTEX-OIZH 1 50-59 0 1 6 Prostate Prostate 2367 157
    GTEX-OOBJ-2026-SM-3NB1R GTEX-OOBJ 1 60-69 0 1 7.2 Prostate Prostate 2367 157
    GTEX-OOBK-2025-SM-3LK5S GTEX-OOBK 1 40-49 0 1 6.1 Prostate Prostate 2367 196
    GTEX-P4QS-2026-SM-3NMCG GTEX-P4QS 1 60-69 0 1 6.1 Prostate Prostate 2367 177
    GTEX-PLZ6-1126-SM-3P5ZR GTEX-PLZ6 1 30-39 0 1 7.3 Prostate Prostate 2367 194
    GTEX-Q2AI-1126-SM-48U19 GTEX-Q2AI 1 40-49 0 1 7.3 Prostate Prostate 2367 153
    GTEX-QEG4-2226-SM-4R1JM GTEX-QEG4 1 30-39 1 2 6.1 Prostate Prostate 2367 978
    GTEX-QLQ7-1326-SM-4R1JY GTEX-QLQ7 1 60-69 0 1 6.8 Prostate Prostate 2367 148
    GTEX-QMRM-1426-SM-4R1K8 GTEX-QMRM 1 50-59 0 1 6.7 Prostate Prostate 2367 165
    GTEX-QV31-1026-SM-4R1K3 GTEX-QV31 1 30-39 0 1 8.3 Prostate Prostate 2367 200
    GTEX-QV44-1526-SM-4R1KI GTEX-QV44 1 50-59 0 1 5.8 Prostate Prostate 2367 163
    GTEX-REY6-2126-SM-48FD9 GTEX-REY6 1 60-69 0 2 7.1 Prostate Prostate 2367 329
    GTEX-RM2N-1126-SM-48FCY GTEX-RM2N 1 50-59 0 1 6.2 Prostate Prostate 2367 174
    GTEX-RWSA-2026-SM-47JX8 GTEX-RWSA 1 40-49 1 1 6.1 Prostate Prostate 2367 1376
    GTEX-S33H-1826-SM-4AD65 GTEX-S33H 1 30-39 2 1 6.1 Prostate Prostate 2367 253
    GTEX-S3XE-1326-SM-4AD4H GTEX-S3XE 1 50-59 0 1 7.8 Prostate Prostate 2367 169
    GTEX-S4Q7-1026-SM-4AD75 GTEX-S4Q7 1 20-29 0 1 8.1 Prostate Prostate 2367 170
    GTEX-S95S-1026-SM-4B64M GTEX-S95S 1 60-69 0 1 6.1 Prostate Prostate 2367 269
    GTEX-SJXC-2026-SM-4DM6N GTEX-SJXC 1 60-69 2 3 5.8 Prostate Prostate 2367 1088
    GTEX-SNMC-0926-SM-4DM5U GTEX-SNMC 1 20-29 0 1 7.1 Prostate Prostate 2367 235
    GTEX-SNOS-1026-SM-4DM4Y GTEX-SNOS 1 40-49 0 1 8 Prostate Prostate 2367 163
    GTEX-SUCS-1126-SM-4DM61 GTEX-SUCS 1 70-79 0 1 7.2 Prostate Prostate 2367 185
    GTEX-T5JC-1226-SM-4DM7C GTEX-T5JC 1 20-29 2 1 6.6 Prostate Prostate 2367 716
    GTEX-T8EM-1826-SM-4DM7F GTEX-T8EM 1 40-49 0 1 5.7 Prostate Prostate 2367 399
    GTEX-U3ZH-0926-SM-4DXU4 GTEX-U3ZH 1 30-39 0 1 6.9 Prostate Prostate 2367 207
    GTEX-U3ZM-0926-SM-4DXSW GTEX-U3ZM 1 40-49 0 1 7.5 Prostate Prostate 2367 231
    GTEX-U412-2026-SM-4DXSI GTEX-U412 1 60-69 3 2 6.2 Prostate Prostate 2367 1397
    GTEX-U4B1-1426-SM-4DXTX GTEX-U4B1 1 40-49 0 1 8 Prostate Prostate 2367 203
    GTEX-U8XE-2526-SM-4E3IT GTEX-U8XE 1 30-39 4 1 7.2 Prostate Prostate 2367 437
    GTEX-UTHO-2726-SM-4JBH9 GTEX-UTHO 1 60-69 3 2 7.5 Prostate Prostate 2367 494
    GTEX-V1D1-1926-SM-4JBGX GTEX-V1D1 1 50-59 0 2 6.7 Prostate Prostate 2367 424
    GTEX-V955-1826-SM-4JBIL GTEX-V955 1 60-69 0 1 5.8 Prostate Prostate 2367 215
    GTEX-VJYA-1226-SM-3GIJ6 GTEX-VJYA 1 60-69 0 1 7.2 Prostate Prostate 2367 258
    GTEX-WFG7-1826-SM-3GIL1 GTEX-WFG7 1 20-29 0 1 8.2 Prostate Prostate 2367 203
    GTEX-WFG8-1826-SM-4LVM4 GTEX-WFG8 1 20-29 0 1 7.7 Prostate Prostate 2367 291
    GTEX-WFON-1626-SM-4LVMV GTEX-WFON 1 40-49 0 1 7.1 Prostate Prostate 2367 207
    GTEX-WH7G-1726-SM-4LVKY GTEX-WH7G 1 40-49 0 2 6.4 Prostate Prostate 2367 324
    GTEX-WK11-2626-SM-4OOSK GTEX-WK11 1 50-59 1 1 5.8 Prostate Prostate 2367 1009
    GTEX-WOFM-0326-SM-4OOSL GTEX-WOFM 1 20-29 0 1 7 Prostate Prostate 2367 171
    GTEX-WY7C-2026-SM-4ONCM GTEX-WY7C 1 50-59 0 1 6.7 Prostate Prostate 2367 216
    GTEX-WYJK-0626-SM-4ONCZ GTEX-WYJK 1 50-59 0 1 7.5 Prostate Prostate 2367 752
    GTEX-WZTO-0926-SM-4PQZ3 GTEX-WZTO 1 40-49 1 1 7.4 Prostate Prostate 2367 510
    GTEX-X5EB-1826-SM-4E3K8 GTEX-X5EB 1 40-49 0 1 8.3 Prostate Prostate 2367 255
    GTEX-XAJ8-0626-SM-47JY4 GTEX-XAJ8 1 40-49 0 1 6.4 Prostate Prostate 2367 143
    GTEX-XGQ4-1826-SM-4AT6F GTEX-XGQ4 1 50-59 0 1 7.2 Prostate Prostate 2367 186
    GTEX-XMK1-1026-SM-4B65H GTEX-XMK1 1 40-49 0 1 7.2 Prostate Prostate 2367 189
    GTEX-XOTO-2826-SM-4B65I GTEX-XOTO 1 50-59 2 2 6.8 Prostate Prostate 2367 715
    GTEX-XPVG-2026-SM-4B65E GTEX-XPVG 1 50-59 0 1 8.3 Prostate Prostate 2367 187
    GTEX-XQ3S-2526-SM-4BOOG GTEX-XQ3S 1 20-29 1 2 6.9 Prostate Prostate 2367 917
    GTEX-XXEK-1226-SM-4BRUY GTEX-XXEK 1 50-59 0 1 6.4 Prostate Prostate 2367 171
    GTEX-Y8E4-2126-SM-5RQHO GTEX-Y8E4 1 40-49 0 1 6.4 Prostate Prostate 2367 425
    GTEX-Y9LG-1826-SM-4VBQC GTEX-Y9LG 1 30-39 0 1 7.1 Prostate Prostate 2367 136
    GTEX-YB5E-1826-SM-5IFI4 GTEX-YB5E 1 40-49 0 1 6.7 Prostate Prostate 2367 238
    GTEX-YF7O-1926-SM-4W1YQ GTEX-YF7O 1 50-59 0 1 7.8 Prostate Prostate 2367 187
    GTEX-YFCO-1626-SM-4W1Z3 GTEX-YFCO 1 40-49 0 1 7.8 Prostate Prostate 2367 172
    GTEX-YJ8A-1126-SM-5IFJU GTEX-YJ8A 1 20-29 0 1 6.9 Prostate Prostate 2367 245
    GTEX-ZDYS-1226-SM-5IJF3 GTEX-ZDYS 1 50-59 0 1 7.5 Prostate Prostate 2367 181
    GTEX-ZEX8-2026-SM-4WKF3 GTEX-ZEX8 1 50-59 0 1 6.4 Prostate Prostate 2367 166
    GTEX-ZLFU-1726-SM-4WWBU GTEX-ZLFU 1 40-49 0 1 5.9 Prostate Prostate 2367 161
    GTEX-ZPU1-2026-SM-57WFI GTEX-ZPU1 1 40-49 0 1 7.8 Prostate Prostate 2367 141
    GTEX-ZT9W-1626-SM-4YCDQ GTEX-ZT9W 1 50-59 0 1 7.8 Prostate Prostate 2367 133
    GTEX-ZTTD-2726-SM-57WFA GTEX-ZTTD 1 50-59 3 3 8.7 Prostate Prostate 2367 379
    GTEX-ZTX8-1026-SM-5EGHD GTEX-ZTX8 1 20-29 0 1 8 Prostate Prostate 2367 159
    GTEX-ZUA1-2826-SM-59HLE GTEX-ZUA1 1 40-49 2 3 6.5 Prostate Prostate 2367 967
    GTEX-ZVP2-0826-SM-59HJ6 GTEX-ZVP2 1 50-59 0 1 6.1 Prostate Prostate 2367 140
    GTEX-ZY6K-1526-SM-5GZXE GTEX-ZY6K 1 50-59 0 1 6.5 Prostate Prostate 2367 208
    GTEX-ZYFD-2526-SM-5E45L GTEX-ZYFD 1 50-59 3 3 6 Prostate Prostate 2367 658
    GTEX-ZZ64-0926-SM-5E44L GTEX-ZZ64 1 20-29 0 0 6.2 Prostate Prostate 2367 192
    Contact

    Department of Biostatistics
    Harvard T.H. Chan School of Public Health

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