GRAND is a collection of gene regulatory networks derived from human tissues, cancer, cell lines, and small molecule drugs. These networks are bipartite graphs linking either transcription factors (TFs) or miRNAs to their target genes. GRAND includes an integrated webserver to test for enrichment of a list of TFs in a set of libraries as well as a tool (CLUEreg) to find compounds that reverse/exacerbate a gene or TF regulatory profile.
Publication: Ben Guebila, Lopes-Ramos et al. NAR, 2022. Current version: 1.6.0. Last update: 09/21/2024.
36 tissue-specific TF and miRNA regulatory networks and 8,279 single-sample networks using data from GTEx.